Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24634014 | 1.00 | PIK3CD (0.39) | PIK3CDATMDPP4DPP8DPP9 | |
| SCHEMBL8895922 | 0.79 | ATM (0.53) | ATMGAA | |
| SCHEMBL5067978 | 0.79 | ATM (0.53) | ATMGAA | |
| SCHEMBL21290883 | 0.79 | ATM (0.53) | ATMGAA | |
| SCHEMBL20158969 | 0.78 | MAOA (0.40) | PIK3CDATMDPP4DPP8DPP9 | |
| SCHEMBL9965183 | 0.78 | ATM (0.39) | PIK3CDATMCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL30148983 | 0.78 | MAOA (0.40) | PIK3CDATMDPP4DPP8DPP9 | |
| SCHEMBL20158970 | 0.78 | MAOA (0.40) | PIK3CDATMDPP4DPP8DPP9 | |
| SCHEMBL24312887 | 0.76 | PIK3CD (0.42) | PIK3CDATMDPP4DPP8DPP9 | |
| SCHEMBL14569611 | 0.76 | PIK3CD (0.42) | PIK3CDATMDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |