Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290883 | 1.00 | ATM (0.53) | ATMCD274PDCD1MMERIPK1 | |
| SCHEMBL8895922 | 1.00 | ATM (0.53) | ATMCD274PDCD1MMERIPK1 | |
| SCHEMBL12155273 | 0.85 | ATM (0.50) | ATMCD274PDCD1GAA | |
| SCHEMBL8894208 | 0.85 | ATM (0.50) | ATMCD274PDCD1GAA | |
| SCHEMBL14355763 | 0.85 | ATM (0.50) | ATMCD274PDCD1GAA | |
| SCHEMBL12191622 | 0.85 | ATM (0.50) | ATMCD274PDCD1GAA | |
| SCHEMBL26999793 | 0.84 | ATM (0.40) | ATMCD274GAA | |
| SCHEMBL21618694 | 0.84 | ATM (0.40) | ATMCD274GAA | |
| SCHEMBL20158970 | 0.82 | MAOA (0.40) | ATMGAA | |
| SCHEMBL9965183 | 0.82 | ATM (0.39) | ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220041583-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-02-10 | — | — | US | disclosed |
| US-8399681-B2 | Substituted aminothiazolone indazoles as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-19 | — | — | US | disclosed |
| US-20120302544-A1 | SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS | BIGNAN GILLES (US) | 2012-11-29 | — | — | US | disclosed |
| US-8172873-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110251364-A1 | Shape Memory Polymers | NATIONAL SCIENCE FOUNDATION | 2011-10-13 | — | — | US | disclosed |
| US-7935131-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2011-05-03 | — | — | US | disclosed |
| US-20080177303-A1 | Shape memory polymers | ROCHESTER, UNIVERSITY OF | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041583-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THERE OF | IL2, TSLP, CD74 | ATM 3177/4885CD274 175/4885PDCD1 348/4885 |
| US-20120302544-A1 | SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS | ESR2, ESRRA, IGF1R | ATM 573/4885CD274 2650/4885PDCD1 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.