SCHEMBL24634342

SCHEMBL24634342

CC(C)(C)c1ccc(N(c2ccc(-c3cccc4c3sc3ccccc34)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
TNKS O95271 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44
PARP14 Q460N5 1/20 0.40
TNF P01375 1/20 0.39
NOD1 Q9Y239 1/20 0.39
PRKDC P78527 2/20 0.35
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
S1PR4 O95977 1/20 0.34
S1PR5 Q9H228 1/20 0.34
GPR3 P46089 1/20 0.33
NR1I2 O75469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19735276 0.92 ALOX5 (0.56) ALOX5TNKSTNKS2PARP14TNF
SCHEMBL12959984 0.90 ALOX5 (0.49) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL74719 0.89 ALOX5 (0.59) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL9890855 0.86 ALOX5 (0.51) ALOX5TNKSTNKS2PARP14TNF
SCHEMBL74716 0.86 ALOX5 (0.56) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL12925533 0.86 ALOX5 (0.56) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL74128 0.86 ALOX5 (0.56) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL75846 0.86 ALOX5 (0.56) ALOX5TNKSTNKS2PARP14PRKDC
SCHEMBL12206310 0.85 ALOX5 (0.44) ALOX5TNKSTNKS2PARP14TNF
SCHEMBL12037224 0.85 ALOX5 (0.52) ALOX5TNKSTNKS2PARP14PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912816-B2 Polymer and light-emitting device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-02-27 US disclosed
US-20220372211-A1 POLYMER AND LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2022-11-24 US disclosed