SCHEMBL74716

SCHEMBL74716

c1ccc(N(c2ccccc2)c2ccc(N(c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
PARP14 Q460N5 1/20 0.43
GPR3 P46089 1/20 0.39
APP P05067 1/20 0.39
PRKDC P78527 4/20 0.39
LIMK1 P53667 2/20 0.38
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
F9 P00740 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PIK3CD O00329 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12925533 1.00 ALOX5 (0.56) ALOX5PARP14GPR3APPPRKDC
SCHEMBL74128 1.00 ALOX5 (0.56) ALOX5PARP14GPR3APPPRKDC
SCHEMBL75846 1.00 ALOX5 (0.56) ALOX5PARP14GPR3APPPRKDC
SCHEMBL75838 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL74452 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL24797069 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL74945 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL16382437 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL75849 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC
SCHEMBL75847 0.98 ALOX5 (0.55) ALOX5PARP14GPR3APPPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-10-15 US disclosed
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-03-14 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885PARP14 1860/4885GPR3 3499/4885
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same EML4, DDC, TYR ALOX5 3471/4885PARP14 1069/4885GPR3 3378/4885
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same ALK, ALKBH3, ACVRL1 ALOX5 1568/4885PARP14 1958/4885GPR3 3038/4885
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, DDC, TYR ALOX5 3471/4885PARP14 1069/4885GPR3 3378/4885
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885PARP14 1860/4885GPR3 3499/4885
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885PARP14 1860/4885GPR3 3499/4885
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885PARP14 1860/4885GPR3 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.