Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 8/20 | 1.00 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.56 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27256179 | 0.91 | ACSL1 (0.84) | ACSL1ACSL3ACSL6ACACBHDAC6 | |
| SCHEMBL23510451 | 0.78 | ACSL1 (0.64) | ACSL1ACACBHDAC6SMN1; SMN2NPC1 | |
| SCHEMBL24634556 | 0.74 | ACSL1 (1.00) | ACSL1ACSL3ACSL6 | |
| SCHEMBL26780273 | 0.72 | ACSL1 (1.00) | ACSL1ACSL3ACSL6NPC1RAB9A | |
| SCHEMBL24634565 | 0.72 | ACSL1 (1.00) | ACSL1ACSL3ACSL6NPC1RAB9A | |
| SCHEMBL28559369 | 0.72 | SMN1; SMN2 (0.66) | ACSL1HDAC6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1749499 | 0.71 | ACSL1 (0.56) | ACSL1ACSL3ACSL6SMN1; SMN2NPC1 | |
| SCHEMBL23034152 | 0.70 | ACSL1 (0.53) | ACSL1ACACBKDM4EALDH1A1POLB | |
| SCHEMBL445014 | 0.69 | HDAC6 (0.74) | HDAC6SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5227432 | 0.69 | ACSL1 (0.53) | ACSL1HDAC6SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | WAVEBREAK INC (US) | 2024-06-27 | — | — | US | disclosed |
| WO-2022212568-A9 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022212568-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207270-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | CPT2, PC, SREBF2 | ACSL1 90/4885ACSL3 129/4885ACSL6 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.