Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PTAFR | P25105 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FES | P07332 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | MARK3 | P27448 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999630 | 0.89 | CYP1A2 (0.68) | TBXAS1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9579533 | 0.87 | CYP3A4 (0.58) | TBXAS1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16353740 | 0.86 | TBXAS1 (0.67) | TBXAS1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2101709 | 0.84 | LMNA (0.77) | MAPTLMNATSHRHPGD | |
| SCHEMBL8422210 | 0.84 | HPGD (0.63) | TBXAS1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16353647 | 0.83 | TBXAS1 (0.61) | TBXAS1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7443753 | 0.83 | TBXAS1 (1.00) | TBXAS1MAPT | |
| SCHEMBL607494 | 0.83 | TBXAS1 (1.00) | TBXAS1MAPT | |
| SCHEMBL1009589 | 0.83 | TBXAS1 (1.00) | TBXAS1MAPT | |
| SCHEMBL16116694 | 0.83 | TBXAS1 (1.00) | TBXAS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251612-A1 | 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2022-12-01 | — | — | WO | disclosed |