Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 6/20 | 0.72 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.61 |
| ▸ | P2RY11 | Q96G91 | 5/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494944 | 1.00 | RNASEL (0.72) | RNASELCA5AP2RY1P2RY11DNPH1 | |
| SCHEMBL29814022 | 0.96 | RNASEL (0.67) | RNASELCA5AP2RY1P2RY11DNPH1 | |
| SCHEMBL16700308 | 0.96 | RNASEL (0.67) | RNASELCA5AP2RY1P2RY11DNPH1 | |
| Water SCHEMBL31186262 | 0.95 | RNASEL (0.66) | RNASELCA5AP2RY1P2RY11DNPH1 | |
| SCHEMBL30047050 | 0.93 | RNASEL (0.75) | RNASELP2RY1P2RY11P2RX3ENPP1 | |
| SCHEMBL195866 | 0.93 | RNASEL (0.75) | RNASELP2RY1P2RY11P2RX3ENPP1 | |
| SCHEMBL2020893 | 0.92 | RNASEL (0.77) | RNASELP2RY1P2RY11SRCP2RY2 | |
| SCHEMBL20266295 | 0.92 | RNASEL (0.61) | RNASELCA5AP2RY1NT5EP2RY12 | |
| SCHEMBL30969952 | 0.92 | RNASEL (0.61) | RNASELCA5AP2RY1NT5EP2RY12 | |
| SCHEMBL29450811 | 0.91 | RNASEL (0.85) | RNASELCA5AP2RY1P2RY11DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940470-B1 | APPARATUS FOR TESTING PLATELET AGGREGATION IN RESPONSE TO A DRUG | UNIV KOREA RES & BUS FOUND (KR) | 2020-03-25 | — | — | EP | claimed |
| US-20190209594-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHEMORESISTANT ACUTE MYELOID LEUKEMIA (AML) | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2019-07-11 | — | — | US | claimed |
| EP-3452092-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHEMORESISTANT ACUTE MYELOID LEUKEMIA (AML) | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2019-03-13 | — | — | EP | claimed |
| CN-104884954-B | Test the device and method of the multi-functional and drug response of the blood platelet based on centrifugal type microfludic method | 高丽大学校产学协力团 | 2018-07-24 | — | — | CN | claimed |
| US-9983220-B2 | Apparatus and method for platelet function and drug response testing based on microfluidic chip | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2018-05-29 | — | — | US | claimed |
| US-9927425-B2 | Apparatus and method for testing multi-function and drug response of centrifugal microfluidic-based platelets | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2018-03-27 | — | — | US | claimed |
| WO-2017191300-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHEMORESISTANT ACUTE MYELOID LEUKEMIA (AML) | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-11-09 | — | — | WO | claimed |
| US-9759730-B2 | Method and device for the determination of platelet function under flow conditions | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2017-09-12 | — | — | US | claimed |
| EP-2645932-B1 | BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT | BECTON DICKINSON CO (US) | 2016-03-02 | — | — | EP | claimed |
| US-20150355167-A1 | APPARATUS AND METHOD FOR TESTING MULTI-FUNCTION AND DRUG RESPONSE OF CENTRIFUGAL MICROFLUIDIC-BASED PLATELETS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2015-12-10 | — | — | US | claimed |
| US-8895259-B2 | Method for determination of platelet function under flow conditions | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2014-11-25 | — | — | US | claimed |
| EP-1850134-B1 | Method and Apparatus for the determination of the Thromboyte function and flow conditions | SIEMENS HEALTHCARE DIAGNOSTICS (DE) | 2013-01-30 | — | — | EP | claimed |
| US-20120149004-A1 | BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT | BECTON, DICKINSON AND COMPANY (US) | 2012-06-14 | — | — | US | claimed |
| EP-1850135-B1 | Method for determining the thrombocyte function and flow conditions | SIEMENS HEALTHCARE DIAGNOSTICS (DE) | 2010-11-03 | — | — | EP | claimed |
| US-20070254324-A1 | Method for determination of platelet function under flow conditions | DADE BEHRING MARBURG GMBH | 2007-11-01 | — | — | US | claimed |
| US-20070254325-A1 | Method and device for the determination of platelet function under flow conditions | DADE BEHRING MARBURG GMBH | 2007-11-01 | — | — | US | claimed |
| EP-1850134-A1 | Method and Apparatus for the determination of the Thromboyte function and flow conditions | Dade Behring Marburg GmbH (DE) | 2007-10-31 | — | — | EP | claimed |
| WO-2005079250-A2 | PURINES ARE SELF-RENEWAL SIGNALS FOR NEURAL STEM CELLS, AND PURINE RECEPTOR ANTAGONISTS PROMOTE NEURONAL AND GLIAL DIFFERENTIATION THEREFROM | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20050181503-A1 | Purines are self-renewal signals for neural stem cells, and purine receptor antagonists promote neuronal and glial differentiation therefrom | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-08-18 | — | — | US | claimed |
| US-20050053612-A1 | Nucleotide regulation of immune responses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-03-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053612-A1 | Nucleotide regulation of immune responses | NT5C2, ENTPD5, ENTPD1 | RNASEL 664/4885CA5A 3820/4885P2RY1 7/4885 |
| US-20120149004-A1 | BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT | FUCA2, HBG1, FUT6 | RNASEL 682/4885CA5A 4748/4885P2RY1 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.