Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401686 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4DNM1TSHR | |
| SCHEMBL3622688 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4DNM1TSHR | |
| SCHEMBL13969948 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4DNM1TSHR | |
| SCHEMBL9486520 | 0.87 | ACE2 (0.41) | ALDH1A1TDP1CYP3A4OPRM1ACE2 | |
| SCHEMBL218869 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4OPRM1DNM1 | |
| SCHEMBL2874916 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4OPRM1DNM1 | |
| SCHEMBL3795911 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4DNM1TSHR | |
| SCHEMBL20248022 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4OPRM1DNM1 | |
| SCHEMBL22604 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4OPRM1DNM1 | |
| SCHEMBL117272 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4OPRM1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251612-A1 | 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2022-12-01 | — | — | WO | disclosed |