Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096041 | 0.82 | PPARA (0.59) | PPARATDP1SMN1; SMN2RECQLTSHR | |
| SCHEMBL11716051 | 0.77 | SMN1; SMN2 (0.54) | PPARATDP1SMN1; SMN2TSHRFFAR1 | |
| SCHEMBL4185056 | 0.76 | TDP1 (0.55) | PPARATDP1SMN1; SMN2RECQLTSHR | |
| SCHEMBL9718320 | 0.74 | TSHR (0.66) | PPARATDP1SMN1; SMN2TSHRHPGD | |
| SCHEMBL11593869 | 0.73 | PPARA (0.59) | PPARATDP1SMN1; SMN2RECQLTSHR | |
| SCHEMBL4185051 | 0.73 | PPARA (0.68) | PPARATDP1SMN1; SMN2RECQLTSHR | |
| Rac-Dichlorprop SCHEMBL28260029 | 0.73 | TSHR (0.68) | PPARASMN1; SMN2TSHRHPGDCYP1A2 | |
| SCHEMBL2412174 | 0.72 | IRAK4 (0.53) | SMN1; SMN2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL31503199 | 0.72 | PPARA (0.71) | PPARATDP1SMN1; SMN2RECQLTSHR | |
| SCHEMBL11591588 | 0.72 | TDP1 (0.58) | PPARATDP1SMN1; SMN2RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012587-B2 | hydrophilic polymer layers bound by means of adhesion promoters, used as immobilization matrix and for the suppression of non-specific protein adsorption in biosensors, MALDI targets and other bioanalytical devices | INSTITUT FUR CHEMO-UND BIOSENSORIK MUNSTER E.V. (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20050042455-A1 | hydrophilic polymer layers bound by means of adhesion promoters, used as immobilization matrix and for the suppression of non-specific protein adsorption in biosensors, MALDI targets and other bioanalytical devices | GEDIG ERK (DE) | 2005-02-24 | — | — | US | disclosed |