Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765923 | 0.85 | PPARD (0.44) | PPARDPPARAFFAR1FFAR4MEN1 | |
| SCHEMBL2463785 | 0.85 | PPARD (0.38) | CTSAWNT3APPARDPPARAS1PR1 | |
| SCHEMBL2463771 | 0.84 | PPARD (0.44) | CTSAWNT3APPARDPPARA | |
| SCHEMBL2493984 | 0.83 | CTSA (0.36) | CTSAWNT3APPARDPPARAS1PR1 | |
| SCHEMBL4754172 | 0.79 | CRHR1 (0.34) | CTSAWNT3APPARDPPARAS1PR1 | |
| SCHEMBL2466105 | 0.78 | PPARD (0.37) | CTSAWNT3APPARDPPARAS1PR1 | |
| SCHEMBL6888377 | 0.78 | THRA (0.38) | CTSAWNT3APPARDPPARAS1PR1 | |
| SCHEMBL3522397 | 0.77 | PPARD (0.42) | PPARDPPARAKDM4EMEN1MAPT | |
| SCHEMBL2465204 | 0.73 | PPARD (0.46) | PPARDPPARAFFAR1FFAR4MEN1 | |
| SCHEMBL2465182 | 0.72 | PPARD (0.47) | CTSAWNT3APPARDPPARAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |