Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 14/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640482 | 1.00 | NPBWR1 (0.48) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL24640499 | 1.00 | NPBWR1 (0.48) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL24640895 | 0.86 | NPBWR1 (0.54) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL24640401 | 0.85 | NPBWR1 (0.43) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL21521227 | 0.82 | NPBWR1 (0.51) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL21521225 | 0.82 | NPBWR1 (0.51) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL24640479 | 0.82 | NPBWR1 (0.51) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL24640501 | 0.79 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29731534 | 0.79 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29102671 | 0.79 | NPBWR1 (0.68) | NPBWR1MCHR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |