Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 13/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29731573 | 0.87 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL24640501 | 0.87 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29102671 | 0.87 | NPBWR1 (0.68) | NPBWR1MCHR1PKMALDH1A1HTT | |
| SCHEMBL27435433 | 0.84 | NPBWR1 (0.54) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL29731363 | 0.82 | NPBWR1 (0.52) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL14844510 | 0.81 | NPBWR1 (0.67) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL26915060 | 0.80 | NPBWR1 (0.61) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL21521858 | 0.80 | NPBWR1 (0.61) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL4681881 | 0.80 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL24640480 | 0.79 | NPBWR1 (0.48) | NPBWR1MCHR1PKMPKLRPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022156708-A1 | PARP7 ENZYME INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-07-28 | — | — | WO | disclosed |