Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016209 | 0.77 | SOS1 (0.46) | SOS1HRH3 | |
| SCHEMBL24640703 | 0.73 | SOS1 (0.41) | SOS1HRH3PIK3CD | |
| SCHEMBL24640038 | 0.73 | SOS1 (0.41) | SOS1HRH3PIK3CD | |
| SCHEMBL24640702 | 0.73 | SOS1 (0.41) | SOS1HRH3PIK3CD | |
| SCHEMBL27420770 | 0.73 | SOS1 (0.35) | SOS1HRH3PIK3CD | |
| SCHEMBL24640624 | 0.72 | SOS1 (0.38) | SOS1 | |
| SCHEMBL24640638 | 0.72 | SOS1 (0.38) | SOS1 | |
| SCHEMBL24640639 | 0.72 | SOS1 (0.38) | SOS1 | |
| SCHEMBL24640623 | 0.72 | SOS1 (0.38) | SOS1 | |
| SCHEMBL24640640 | 0.72 | SOS1 (0.38) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |