SCHEMBL24640993

SCHEMBL24640993

c1ccc(-n2c3ccc(-c4ccc5c(c4)c4c6sc7ccccc7c6ccc4n5-c4ccccc4)cc3c3c4sc5ccccc5c4ccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 1/20 0.38
JAK2 O60674 1/20 0.37
JAK3 P52333 1/20 0.37
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR3 P46089 1/20 0.34
MAPT P10636 4/20 0.33
ALDH1A1 P00352 2/20 0.33
LIMK1 P53667 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24937500 0.99 ATM (0.40) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL27012134 0.97 ATM (0.39) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL16641286 0.96 ATM (0.45) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL23862324 0.95 ATM (0.44) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL16133217 0.94 ALOX5 (0.37) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL23862279 0.93 L3MBTL1 (0.42) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL14979076 0.93 KDM4E (0.36) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL16133221 0.93 ALOX5 (0.36) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL15137668 0.93 L3MBTL1 (0.42) ATMKDM4EL3MBTL1ALOX5JAK2
SCHEMBL14789658 0.93 KDM4E (0.36) ATMKDM4EL3MBTL1ALOX5JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026341-A1 LIGHT-EMITTING DEVICE, DISPLAY APPARATUS, LIGHT-EMITTING APPARATUS, ELECTRONIC APPLIANCE, AND LIGHTING APPARATUS SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
US-20220320470-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-10-06 US disclosed
US-20220278292-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-09-01 US disclosed