Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.82 |
| ▸ | CA12 | O43570 | 6/20 | 0.82 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.82 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.82 |
| ▸ | CA1 | P00915 | 4/20 | 0.82 |
| ▸ | GLA | P06280 | 3/20 | 0.82 |
| ▸ | GAA | P10253 | 3/20 | 0.82 |
| ▸ | HPGD | P15428 | 3/20 | 0.82 |
| ▸ | CASP1 | P29466 | 3/20 | 0.82 |
| ▸ | CASP7 | P55210 | 3/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.82 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Esculetin SCHEMBL8415100 | 0.92 | CA9 (0.70) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL29569228 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL6867015 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL24641 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Umbelliferone SCHEMBL29624448 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Umbelliferone SCHEMBL22018 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Umbelliferone SCHEMBL29396070 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Umbelliferone SCHEMBL11137587 | 0.91 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL1736697 | 0.89 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL30120615 | 0.89 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870082-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023684-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 1997-07-03 | — | — | WO | disclosed |