Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330070 | 0.90 | CTSS (0.52) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL18477610 | 0.89 | CTSS (0.49) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL20345236 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL20880680 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL18477606 | 0.88 | OPRD1 (0.51) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL27381707 | 0.88 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL25148131 | 0.88 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL24774075 | 0.88 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL25774591 | 0.88 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL24642881 | 0.86 | CTSS (0.46) | CTSSCTSLCTSBOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |