Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642686 | 0.95 | ECE1 (0.36) | ECE1SIRT2ALDH1A1LMNAMAPT | |
| SCHEMBL24642307 | 0.92 | SIRT2 (0.38) | ECE1SIRT2ALDH1A1LMNAMAPT | |
| SCHEMBL24642558 | 0.91 | FAAH (0.34) | ECE1SIRT2ALDH1A1LMNAMAPT | |
| SCHEMBL24642922 | 0.91 | SIRT1 (0.34) | SIRT2DRD2DRD4DRD3CTSS | |
| SCHEMBL24642472 | 0.90 | SIRT1 (0.32) | SIRT2DRD2DRD4DRD3CTSS | |
| SCHEMBL26542866 | 0.89 | SIRT2 (0.33) | SIRT2DRD2DRD4DRD3CTSS | |
| SCHEMBL24642327 | 0.88 | SIRT2 (0.34) | SIRT2SIRT1SIRT6FURINPRSS1 | |
| SCHEMBL24642832 | 0.87 | ECE1 (0.38) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL26499410 | 0.86 | SIRT1 (0.37) | SIRT2CTSSCTSKSIRT1SIRT3 | |
| SCHEMBL24642579 | 0.85 | SIRT1 (0.34) | SIRT2CTSSCTSKSIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |