⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895666 | 1.00 | — | — | |
| SCHEMBL1727737 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL27519050 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL27566668 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL1729387 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL5973715 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL5974127 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL5973999 | 0.97 | ALDH1A1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL447932 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL27501045 | 0.97 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333135-A | Synthesis technology of benthiavalicarb isopropyl | UNIV SHANGQIU NORMAL | 2013-10-02 | — | — | CN | claimed |
| CN-101293878-B | Benzothiazole amino benzenes compounds, preparation method and application thereof | SHANGHAI INST APPLIED PHYSICS | 2010-12-15 | — | — | CN | claimed |
| CN-101293878-A | Benzothiazole amino benzenes compounds, preparation method and application thereof | SHANGHAI INST OF PHYSICS CAS (CN) | 2008-10-29 | — | — | CN | claimed |
| WO-2025077767-A1 | NOVEL I-TYPE TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |
| WO-2024200263-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS α-SYNUCLEIN BINDING COMPOUNDS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2024-10-03 | — | — | WO | disclosed |
| EP-4438597-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS A-SYNUCLEIN BINDING COMPOUNDS | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2024-10-02 | — | — | EP | disclosed |
| EP-4298097-A1 | BENZOTHIAZOLYL BICYCLO[1.1.1]PENTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-20230391764-A1 | BENZOTHIAZOLYL BICYCLO[1.1.1]PENTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-12-07 | — | — | US | disclosed |
| CN-116897155-A | Benzothiazolyl bicyclo [1.1.1] pentane derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-10-17 | — | — | CN | disclosed |
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2023-05-11 | — | — | US | disclosed |
| EP-0115394-B1 | PHENOTHIAZONE DERIVATIVES AND ANALOGS | MERCK FROSST CANADA INC. (CA) | 1989-06-28 | — | — | EP | disclosed |
| US-4594342-A | Anticoagulants | TANABE SEIYAKU CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0158340-A2 | Novel 1,5-benzothiazepine derivative, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0155623-A2 | Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition | MERCK & CO. INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0115394-A2 | Phenothiazone derivatives and analogs | MERCK FROSST CANADA INC. (CA) | 1984-08-08 | — | — | EP | disclosed |
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |