SCHEMBL27501045

SCHEMBL27501045

Nc1ccc(F)cc1S.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
KEAP1 Q14145 1/20 0.43
BACE1 P56817 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
FADS1 O60427 1/20 0.33
CCNE2 O96020 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC1 Q13547 2/20 0.32
AXL P30530 1/20 0.32
GFER P55789 1/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
CA3 P07451 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464299 0.97
SCHEMBL29895666 0.97
SCHEMBL1727737 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL5973715 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL27566668 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL1729387 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL5974127 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL5973999 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
Hydrochloric Acid SCHEMBL447932 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT
SCHEMBL27518815 0.95 ALDH1A1 (0.54) ALDH1A1KEAP1BACE1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1235891-C Process for producing substituted alkylamine derivative IHARA CHEMICAL IND CO (JP) 2006-01-11 CN disclosed
CN-1366522-A Process for producing substituted alkylamine derivative IHARA CHEMICAL IND CO (JP) 2002-08-28 CN disclosed