Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.66 |
| ▸ | MMP2 | P08253 | 2/20 | 0.66 |
| ▸ | MMP9 | P14780 | 2/20 | 0.66 |
| ▸ | MMP8 | P22894 | 2/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996999 | 0.88 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2628260 | 0.88 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL31120302 | 0.83 | APP (0.81) | APPMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2461783 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL21043886 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL31592008 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL10311768 | 0.83 | RORC (0.71) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2062033 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2119612 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL4224543 | 0.82 | APP (0.86) | APPMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108187044-B | Neutron capture therapy system for eliminating beta amyloid | 南京中硼联康医疗科技有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-108239101-B | Compound for preparing compound specifically binding with beta amyloid, preparation method and application thereof | 南京中硼联康医疗科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-108440584-B | Process for the preparation of intermediates useful in the preparation of compounds that specifically bind to β amyloid | 南京中硼联康医疗科技有限公司 | 2020-08-07 | — | — | CN | claimed |
| US-10709783-B2 | Neutron capture therapy system for eliminating amyloid β-protein | NEUBORON MEDTECH LTD. (CN) | 2020-07-14 | — | — | US | claimed |
| US-10683310-B2 | Compound for specifically binding to amyloid β-protein | NEUBORON MEDTECH LTD. (CN) | 2020-06-16 | — | — | US | claimed |
| CN-108276435-B | Process for the preparation of intermediates useful in the preparation of compounds that specifically bind to β amyloid | 南京中硼联康医疗科技有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-108395446-B | Method for preparing compound specifically binding to β amyloid | 南京中硼联康医疗科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| EP-3385266-B1 | COMPOUND FOR SPECIFIC BINDING WITH AMYLOID BETA-PROTEIN | NEUBORON MEDTECH LTD (CN) | 2019-08-14 | — | — | EP | claimed |
| EP-3384960-B1 | NEUTRON CAPTURE THERAPY SYSTEM FOR ELIMINATING AMYLOID ß-PROTEIN | NEUBORON MEDTECH LTD (CN) | 2019-06-05 | — | — | EP | claimed |
| US-10239895-B2 | Compound for specifically binding to amyloid β-protein | NEUBORON MEDTECH LTD. (CN) | 2019-03-26 | — | — | US | claimed |
| EP-3385266-A1 | COMPOUND FOR SPECIFIC BINDING WITH AMYLOID PROTEIN | Neuboron Medtech Ltd. (CN) | 2018-10-10 | — | — | EP | claimed |
| CN-108530473-A | With the compound of amyloid beta specific binding | 南京中硼联康医疗科技有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-108440584-A | It is used to prepare the preparation method of the intermediate of the compound specifically bound with amyloid beta | 南京中硼联康医疗科技有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-108395446-A | With the preparation method of the compound of amyloid beta specific binding | 南京中硼联康医疗科技有限公司 | 2018-08-14 | — | — | CN | claimed |
| CN-108276435-A | It is used to prepare the preparation method of the intermediate of the compound specifically bound with amyloid beta | 南京中硼联康医疗科技有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-108239101-A | It is used to prepare compound, the preparation method and applications of the compound specifically bound with amyloid beta | 南京中硼联康医疗科技有限公司 | 2018-07-03 | — | — | CN | claimed |
| CN-108187044-A | For eliminating the neutron capture treatment system of amyloid beta | 南京中硼联康医疗科技有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-106730414-B | Neutron capture therapy system for eliminating beta amyloid | 南京中硼联康医疗科技有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-106730414-A | Neutron capture therapy system for eliminating beta amyloid | 南京中硼联康医疗科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106674265-A | Compounds that specifically bind to amyloid beta | 南京中硼联康医疗科技有限公司 | 2017-05-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10709783-B2 | Neutron capture therapy system for eliminating amyloid β-protein | NUCB2, APP, BACE1 | APP 2/4885MMP2 1209/4885MMP9 1870/4885 |
| US-10683310-B2 | Compound for specifically binding to amyloid β-protein | APP, NUCB2, BACE1 | APP 1/4885MMP2 1682/4885MMP9 2829/4885 |
| US-10239895-B2 | Compound for specifically binding to amyloid β-protein | APP, NUCB2, BACE1 | APP 1/4885MMP2 1682/4885MMP9 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.