Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.66 |
| ▸ | MMP8 | P22894 | 1/20 | 0.66 |
| ▸ | MMP13 | P45452 | 1/20 | 0.66 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461783 | 1.00 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2628260 | 0.88 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL1996999 | 0.88 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2464396 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2119612 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL10311768 | 0.83 | RORC (0.71) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL19149792 | 0.83 | APP (0.62) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2062033 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL21043886 | 0.83 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL11973034 | 0.83 | APP (0.61) | APPMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912563-B | Benzo five-membered nitrogen heterocyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-27 | — | — | CN | disclosed |