Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 13/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24644929 | 1.00 | HCRTR2 (0.36) | HCRTR2IDH1TP53GRM5NPC1 | |
| SCHEMBL27354517 | 0.92 | IDH1 (0.34) | IDH1TP53NPC1RAB9A | |
| SCHEMBL24644926 | 0.91 | TP53 (0.42) | IDH1TP53 | |
| SCHEMBL24644639 | 0.91 | TP53 (0.33) | IDH1TP53 | |
| SCHEMBL24644869 | 0.91 | PTGDR2 (0.42) | TP53GRM5NPC1HPGDRAB9A | |
| SCHEMBL24645058 | 0.91 | TP53 (0.45) | IDH1TP53GRM5HPGDSMN1; SMN2 | |
| SCHEMBL24644822 | 0.91 | ALOX5AP (0.38) | IDH1TP53 | |
| SCHEMBL24645127 | 0.90 | FAAH (0.40) | IDH1TP53RAB9A | |
| SCHEMBL24645059 | 0.90 | EGLN1 (0.36) | TP53NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL27354451 | 0.90 | EGLN1 (0.36) | TP53NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167445-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-08-11 | — | — | WO | disclosed |