Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24644926 | 0.93 | TP53 (0.42) | FAAHTP53POLBIDH1KDM4E | |
| SCHEMBL24645060 | 0.90 | FAAH (0.42) | FAAHTP53POLBRXFP1IDH1 | |
| SCHEMBL24644880 | 0.90 | FAAH (0.42) | FAAHTP53POLBRXFP1IDH1 | |
| SCHEMBL24644643 | 0.90 | HCRTR2 (0.36) | TP53IDH1RAB9A | |
| SCHEMBL24644929 | 0.90 | HCRTR2 (0.36) | TP53IDH1RAB9A | |
| SCHEMBL27354517 | 0.88 | IDH1 (0.34) | TP53IDH1FFAR1KDM4EGAA | |
| SCHEMBL24645058 | 0.87 | TP53 (0.45) | FAAHTP53POLBIDH1FFAR1 | |
| SCHEMBL24644822 | 0.87 | ALOX5AP (0.38) | TP53IDH1 | |
| SCHEMBL24644639 | 0.87 | TP53 (0.33) | TP53IDH1 | |
| SCHEMBL24644869 | 0.87 | PTGDR2 (0.42) | TP53SOD1FFAR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167445-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-08-11 | — | — | WO | disclosed |