SCHEMBL24644841

SCHEMBL24644841

c1nc(OCC2COCCO2)cc2c1OCCO2

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 20/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24644783 0.78 GPR84 (0.41) GPR84
SCHEMBL24644774 0.75 GRM4 (0.37) GPR84
SCHEMBL20745885 0.73 KDM4E (0.44) GPR84
SCHEMBL20745609 0.70 GPR84 (0.40) GPR84
SCHEMBL24644838 0.69 ALDH1A1 (0.39) GPR84
SCHEMBL840394 0.69 MAPT (0.50) GPR84
SCHEMBL24644612 0.69 GPR84 (0.44) GPR84
SCHEMBL24644768 0.68 GPR84 (0.43) GPR84
SCHEMBL24644819 0.66 TP53 (0.49) GPR84
SCHEMBL21940508 0.65 GPR84 (0.41) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022167445-A1 GPR84 ANTAGONISTS AND USES THEREOF Liminal Biosciences Limited (GB) 2022-08-11 WO disclosed