Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24645036 | 0.91 | TP53 (0.33) | ACACBTP53IDH1FFAR1 | |
| SCHEMBL24644928 | 0.90 | TP53 (0.33) | ACACBTP53IDH1 | |
| SCHEMBL24644661 | 0.89 | TP53 (0.32) | ACACBTP53IDH1 | |
| SCHEMBL24644660 | 0.87 | TP53 (0.34) | TP53PTGDR2IDH1FFAR1 | |
| SCHEMBL24645112 | 0.87 | KDM4E (0.38) | TP53FFAR1 | |
| SCHEMBL24644659 | 0.87 | TP53 (0.31) | ACACBTP53 | |
| SCHEMBL24644808 | 0.86 | BACE1 (0.34) | TP53 | |
| SCHEMBL24644643 | 0.86 | HCRTR2 (0.36) | TP53IDH1 | |
| SCHEMBL24644929 | 0.86 | HCRTR2 (0.36) | TP53IDH1 | |
| SCHEMBL27354517 | 0.85 | IDH1 (0.34) | TP53PTGDR2IDH1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167445-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-08-11 | — | — | WO | disclosed |