Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24644660 | 0.89 | TP53 (0.34) | FFAR1TP53 | |
| SCHEMBL24645036 | 0.88 | TP53 (0.33) | FFAR1TP53 | |
| SCHEMBL24644929 | 0.88 | HCRTR2 (0.36) | TP53GRM5 | |
| SCHEMBL24644643 | 0.88 | HCRTR2 (0.36) | TP53GRM5 | |
| SCHEMBL24644928 | 0.87 | TP53 (0.33) | TP53 | |
| SCHEMBL24645017 | 0.87 | ACACB (0.33) | FFAR1TP53 | |
| SCHEMBL27354517 | 0.86 | IDH1 (0.34) | KDM4EGAAMAPTFFAR1HTT | |
| SCHEMBL24644926 | 0.86 | TP53 (0.42) | KDM4ECYP3A4TP53MET | |
| SCHEMBL24644822 | 0.85 | ALOX5AP (0.38) | MAOBTP53 | |
| SCHEMBL24645058 | 0.85 | TP53 (0.45) | KDM4EGAAMAPTFFAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167445-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-08-11 | — | — | WO | disclosed |