Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464658 | 0.91 | KDM4E (0.33) | MAPK9MAPK8 | |
| SCHEMBL17797219 | 0.90 | LMNA (0.36) | LMNAHTTMAPK9MAPK8MAPK10 | |
| SCHEMBL2466895 | 0.85 | MAPK9 (0.38) | MAPK9MAPK8MAPK10PRKD2MAPK1 | |
| SCHEMBL2470878 | 0.84 | NQO2 (0.32) | — | |
| SCHEMBL2467726 | 0.84 | PDCD1LG2 (0.31) | MAPK9MAPK8 | |
| SCHEMBL2467774 | 0.84 | KDM4E (0.33) | MAPK9MAPK8 | |
| SCHEMBL3328434 | 0.84 | LMNA (0.36) | LMNAHTTMAPK9MAPK8MAPK10 | |
| SCHEMBL2465634 | 0.83 | MAPK9 (0.38) | MAPK9MAPK8MAPK10PRKD2MAPK1 | |
| SCHEMBL2466386 | 0.82 | PDCD1LG2 (0.30) | — | |
| SCHEMBL2467547 | 0.82 | NQO2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |