SCHEMBL2467547

SCHEMBL2467547

COC(=O)Oc1nc(-c2c(F)cc(Cl)c(N(C)C)c2F)cc(N)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469353 0.89 FFAR4 (0.31)
SCHEMBL2470878 0.86 NQO2 (0.32) NQO2
SCHEMBL2464658 0.86 KDM4E (0.33) NQO2
SCHEMBL3454144 0.83 FFAR4 (0.32) NQO2
SCHEMBL3324334 0.83 NQO2 (0.36) NQO2
SCHEMBL2467726 0.82 PDCD1LG2 (0.31) NQO2
SCHEMBL2467774 0.82 KDM4E (0.33) NQO2
SCHEMBL2464677 0.82 LMNA (0.35)
SCHEMBL3454758 0.81 PDCD1LG2 (0.31)
SCHEMBL2469352 0.80 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2939540-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2369929-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 EP disclosed
WO-2010060581-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO disclosed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP disclosed