Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293131 | 0.83 | CA1 (0.53) | CA1CA2HTR6MTNR1AMTNR1B | |
| SCHEMBL29655195 | 0.78 | HTR6 (0.56) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL1567620 | 0.78 | MTNR1A (0.54) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL7379841 | 0.78 | HTR6 (0.56) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL15882484 | 0.74 | MTNR1A (0.55) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL17335656 | 0.74 | MTNR1A (0.55) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL7167235 | 0.74 | HTR6 (0.51) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL29547256 | 0.74 | BCHE (0.56) | HTR6MTNR1AMTNR1BBCHEMAOA | |
| SCHEMBL1567623 | 0.74 | MTNR1A (0.54) | HTR6MTNR1AMTNR1BBCHEIDO1 | |
| SCHEMBL6248217 | 0.74 | HTR6 (0.51) | HTR6MTNR1AMTNR1BBCHEIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4782252-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |