Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 7/20 | 0.98 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.71 |
| ▸ | PDE5A | O76074 | 2/20 | 0.60 |
| ▸ | ACP1 | P24666 | 2/20 | 0.60 |
| ▸ | GBA1 | P04062 | 4/20 | 0.59 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.57 |
| ▸ | OGG1 | O15527 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896250 | 1.00 | MERTK (0.98) | MERTKNPY5RPDE5AACP1GBA1 | |
| SCHEMBL27224044 | 0.91 | MERTK (0.81) | MERTKNPY5RPDE5AACP1GBA1 | |
| SCHEMBL27223950 | 0.89 | MERTK (0.78) | MERTKNPY5RPDE5AACP1GBA1 | |
| SCHEMBL8889634 | 0.88 | MERTK (0.98) | MERTKNPY5RPDE5AACP1TLR7 | |
| SCHEMBL27223364 | 0.88 | MERTK (0.76) | MERTKNPY5RPDE5AACP1TLR7 | |
| SCHEMBL27223511 | 0.87 | MERTK (0.75) | MERTKNPY5RPDE5AACP1GBA1 | |
| SCHEMBL24649804 | 0.87 | MERTK (0.75) | MERTKNPY5RPDE5AACP1GBA1 | |
| SCHEMBL30896206 | 0.87 | MERTK (0.75) | MERTKNPY5RPDE5AACP1GBA1 | |
| Hydrochloric Acid SCHEMBL8890334 | 0.87 | MERTK (0.95) | MERTKNPY5RPDE5AACP1TLR7 | |
| SCHEMBL14256556 | 0.84 | MERTK (0.81) | MERTKNPY5RPDE5AACP1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
| WO-2022173743-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING, OR AMELIORATING AIRWAY DISEASE | THOMAS JEFFERSON UNIVERSITY (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | MERTK 3423/4885NPY5R 2011/4885PDE5A 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.