Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738205 | 1.00 | GPR119 (0.49) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL24649853 | 1.00 | GPR119 (0.49) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL16339346 | 0.89 | GPR119 (0.51) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL24649851 | 0.88 | HDAC1 (0.51) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL24649916 | 0.88 | HDAC1 (0.51) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL25916778 | 0.88 | HDAC1 (0.51) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL25738206 | 0.88 | MAP4K4 (0.52) | GPR119HDAC1MAP4K4NR1H2NR1H3 | |
| SCHEMBL25738081 | 0.87 | NR1H2 (0.58) | GPR119HDAC1NR1H2NR1H3HRH3 | |
| SCHEMBL25738094 | 0.86 | NR1H2 (0.47) | GPR119HDAC1NR1H2NR1H3HRH3 | |
| SCHEMBL12306721 | 0.86 | GPR119 (0.46) | GPR119HDAC1NR1H2NR1H3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |
| WO-2022222995-A1 | PICOLINAMIDE COMPOUND | 南京明德新药研发有限公司 | 2022-10-27 | — | — | WO | disclosed |