Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 14/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738095 | 0.89 | MEN1 (0.45) | NR1H2NR1H3MEN1MAPTTSHR | |
| SCHEMBL25738205 | 0.86 | GPR119 (0.49) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL24649853 | 0.86 | GPR119 (0.49) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL24649915 | 0.86 | GPR119 (0.49) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL25738081 | 0.84 | NR1H2 (0.58) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL31612861 | 0.84 | HRH3 (0.48) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL12306721 | 0.84 | GPR119 (0.46) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL25738475 | 0.83 | GPR119 (0.45) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL25738087 | 0.83 | GPR119 (0.45) | NR1H2NR1H3GPR119HRH3MEN1 | |
| SCHEMBL25738176 | 0.83 | GPR119 (0.45) | NR1H2NR1H3GPR119HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |