Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650728 | 0.95 | FFAR4 (0.40) | FFAR4FFAR1TSHRPPARDHTR2A | |
| SCHEMBL24650259 | 0.89 | FFAR1 (0.41) | FFAR4FFAR1TSHRPPARDPTGDR2 | |
| SCHEMBL24650394 | 0.89 | MCL1 (0.42) | FFAR4FFAR1TSHRPPARDHTR2A | |
| SCHEMBL24650824 | 0.88 | BRD4 (0.43) | MEN1KMT2A | |
| SCHEMBL24650816 | 0.88 | MAPT (0.41) | ACHECNR1CNR2KMT2A | |
| SCHEMBL24650745 | 0.88 | PPARD (0.40) | FFAR4FFAR1TSHRPPARDACHE | |
| SCHEMBL24651079 | 0.84 | SQSTM1 (0.41) | FFAR4FFAR1TSHRPPARDHTR2A | |
| SCHEMBL24651159 | 0.84 | L3MBTL1 (0.37) | ACHECNR1CNR2KMT2A | |
| SCHEMBL24650379 | 0.84 | L3MBTL1 (0.43) | FFAR1TSHRPPARDALOX15HSD17B10 | |
| SCHEMBL24650737 | 0.83 | TSHR (0.44) | FFAR4FFAR1TSHRPPARDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |