Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651042 | 0.93 | PPARD (0.47) | PPARDCHRNB2CHRNA4FFAR1FFAR4 | |
| SCHEMBL24650426 | 0.91 | PPARD (0.42) | PPARDFFAR1FFAR4L3MBTL1MAPT | |
| SCHEMBL24650433 | 0.90 | PPARD (0.41) | PPARDCHRNB2CHRNA4L3MBTL1MAPT | |
| SCHEMBL24650422 | 0.89 | PPARD (0.42) | PPARDCHRNB2CHRNA4FFAR1FFAR4 | |
| SCHEMBL24650316 | 0.89 | BRD4 (0.42) | PPARDCHRNB2CHRNA4FFAR1L3MBTL1 | |
| SCHEMBL24651046 | 0.85 | PPARD (0.42) | PPARDCHRNB2CHRNA4FFAR1FFAR4 | |
| SCHEMBL24651040 | 0.84 | FFAR4 (0.45) | PPARDFFAR1FFAR4L3MBTL1MAPT | |
| SCHEMBL24650543 | 0.84 | CHRNB2 (0.40) | PPARDCHRNB2CHRNA4L3MBTL1MAPT | |
| SCHEMBL24651039 | 0.82 | FFAR1 (0.44) | PPARDFFAR1FFAR4PPARAHTR2A | |
| SCHEMBL24650427 | 0.82 | PYGL (0.38) | CHRNB2CHRNA4MAPTHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |