Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650885 | 0.97 | NAMPT (0.38) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24650495 | 0.92 | TDP1 (0.40) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24650278 | 0.92 | NOTUM (0.37) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24650872 | 0.89 | HTR1A (0.40) | NAMPTTDP1CTDSP1PDE4APDE4B | |
| SCHEMBL24651136 | 0.87 | PPARG (0.38) | TDP1ALDH1A1L3MBTL1ACHE | |
| SCHEMBL24651100 | 0.85 | L3MBTL1 (0.40) | TDP1L3MBTL1ACHE | |
| SCHEMBL24650492 | 0.84 | TDP1 (0.38) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24650864 | 0.84 | NAMPT (0.39) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24650857 | 0.82 | NAMPT (0.45) | NAMPTTDP1ALDH1A1USP2ALOX15 | |
| SCHEMBL24651101 | 0.82 | L3MBTL1 (0.42) | TDP1L3MBTL1CYP1A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |