Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ADK | P55263 | 11/20 | 0.54 |
| ▸ | SRC | P12931 | 5/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | ABL2 | P42684 | 2/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999095 | 1.00 | MTOR (0.55) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL27088114 | 0.89 | SRC (0.65) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL29999242 | 0.89 | SRC (0.65) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL24251862 | 0.89 | SRC (0.65) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL30767877 | 0.87 | SRC (0.57) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL16237288 | 0.86 | SRC (0.59) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL19743649 | 0.86 | FGR (0.57) | MTORRAB9AADKSRCEGFR | |
| Hydrochloric Acid SCHEMBL29999025 | 0.85 | FGR (0.56) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL400626 | 0.84 | SRC (0.61) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL30155310 | 0.84 | ABL1 (0.64) | MTORRAB9AADKSRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240382488-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-11-21 | — | — | US | disclosed |
| US-20240317758-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-09-26 | — | — | US | disclosed |
| CN-117597346-A | NEK7 inhibitors | 哈利亚治疗公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-4320127-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216680-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382488-A1 | NEK7 INHIBITORS | NEK7, NEK11, NEK2 | MTOR 2067/4885RAB9A 1120/4885ADK 168/4885 |
| US-20240317758-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | MTOR 1341/4885RAB9A 3236/4885ADK 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.