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FGR

Tyrosine-protein kinase Fgr · P09769 · FGR on Sugi Atlas →

57,940 patent compounds predicted against FGR, 50,427 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL201744 SCHEMBL201744 1.00 2/20
SCHEMBL201745 SCHEMBL201745 1.00 2/20
SCHEMBL147331 SCHEMBL147331 0.91 2/20
SCHEMBL141930 SCHEMBL141930 0.90 2/20
SCHEMBL142206 SCHEMBL142206 0.85 2/20
SCHEMBL202187 SCHEMBL202187 0.81 2/20
SCHEMBL144842 SCHEMBL144842 0.80 2/20
SCHEMBL144192 SCHEMBL144192 0.75 2/20
SCHEMBL144525 SCHEMBL144525 0.71 2/20
SCHEMBL146263 SCHEMBL146263 0.71 2/20
SCHEMBL141676 SCHEMBL141676 0.69 2/20
SCHEMBL145500 SCHEMBL145500 0.69 2/20
SCHEMBL144281 SCHEMBL144281 0.68 2/20
SCHEMBL141372 SCHEMBL141372 0.68 2/20
SCHEMBL145902 SCHEMBL145902 0.67 2/20
SCHEMBL146743 SCHEMBL146743 0.67 2/20
SCHEMBL144785 SCHEMBL144785 0.67 2/20
SCHEMBL147096 SCHEMBL147096 0.63 2/20
SCHEMBL144209 SCHEMBL144209 0.62 2/20
SCHEMBL144321 SCHEMBL144321 0.61 2/20

Clinical trials — most relevant to FGR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pentaerithrityl Tetranitrate (PETN) for Secondary Prevention of Intrauterine Growth Restriction PHASE3UNKNOWN
Transplacental Aspirin Therapy for Early Onset Fetal Growth Restriction PHASE3WITHDRAWN
LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth) PHASE3ENROLLING_BY_INVITATION
Phase II Dasatinib Study in Advanced Breast Cancer PHASE2COMPLETED
TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea PHASE1COMPLETED
A Cohort of Maternal Vascular Malperfusion-related FGR (CoMVMFGR) nanRECRUITING
The Role of FGL2-FcgammaRIIB Inhibitory Pathway in Human Viral Hepatitis nanCOMPLETED
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation nanUNKNOWN
Evaluation of HALP Score in Distinction Between FGR and SGA nanCOMPLETED
AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study nanRECRUITING
Placental Imaging Techniques nanRECRUITING
STV Analysis Versus Visual Evaluation of Cardiotocography in FGR nanNOT_YET_RECRUITING
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR) nanRECRUITING
Fetal Cardiac Function nanCOMPLETED
Role of Inflammatory Markers and Doppler Parameters in Late-Onset Fetal Growth Restriction: A Machine Learning Approach nanACTIVE_NOT_RECRUITING
EVERREST Developing a Therapy for Fetal Growth Restriction nanCOMPLETED
Long-term Follow-up of Children Born in the PETN Studies nanRECRUITING
Maternal Serum Vascular Endothelial Growth Factor in Pregnant Women With Foetal Growth Restriction nanUNKNOWN
Cardiometabolic Health in First Time Pregnancy nanRECRUITING
Genomic and Epigenomic Alterations After Cancer Treatment in Pregnancy nanUNKNOWN
Placental Growth Factor as a Predictor of Adverse Pregnancy Outcomes in Preeclamptic Women nanCOMPLETED
First-trimester Placental Ultrasound Study nanCOMPLETED
Diastolic Deceleration Area in Early-onset FGR nanUNKNOWN
Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies nanRECRUITING
Pulmonary Artery Doppler in Preeclamptic Mothers nanCOMPLETED
Sildenafil in Sever Intrauterine Growth Retardation nanCOMPLETED
Management of Early-onset Fetal Growth Restriction: Angiogenic Factors Versus Feto-placental Doppler nanNOT_YET_RECRUITING
The Impact of Extreme Environmental and Security Conditions on Prematurity and Low Birth Weight Rates nanACTIVE_NOT_RECRUITING
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally nanUNKNOWN
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a FGR binder may also engage these)

ProteinNameSimilarity
P14234 — 1.000 P14234 →
Q6EWH2 — 1.000 Q6EWH2 →
Q6P6U0 — 1.000 Q6P6U0 →
FYN Tyrosine-protein kinase Fyn 1.000 landscape →
Q62844 — 1.000 Q62844 →
P13116 — 1.000 P13116 →
Q02977 — 1.000 Q02977 →
P50545 — 1.000 P50545 →
P06240 — 1.000 P06240 →
P10936 — 1.000 P10936 →
P00526 — 1.000 P00526 →
P63185 — 1.000 P63185 →
Q5PXS1 — 1.000 Q5PXS1 →
A1Y2K1 — 0.999 A1Y2K1 →
P13115 — 0.999 P13115 →
Q01621 — 0.999 Q01621 →
P00525 — 0.998 P00525 →
P39688 — 0.998 P39688 →
P00527 — 0.998 P00527 →
P25020 — 0.998 P25020 →
HCK Tyrosine-protein kinase HCK 0.997 landscape →
P31693 — 0.997 P31693 →
Q05876 — 0.997 Q05876 →
A1A5H8 — 0.997 A1A5H8 →
P00524 — 0.997 P00524 →
SRC Proto-oncogene tyrosine-protein kinase Src 0.997 landscape →
Q28923 — 0.996 Q28923 →
P00523 — 0.996 P00523 →
P14085 — 0.996 P14085 →
YES1 Tyrosine-protein kinase Yes 0.996 landscape →