SCHEMBL246507

SCHEMBL246507

NNc1ccc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505965 1.00
Hydrochloric Acid SCHEMBL15528342 0.98 FDPS (0.46)
SCHEMBL11158370 0.83 NPC1 (0.44)
SCHEMBL355054 0.80 ALDH1A1 (0.50)
SCHEMBL30057293 0.76
SCHEMBL8503997 0.76
SCHEMBL12952692 0.76
SCHEMBL8503999 0.76
SCHEMBL182965 0.76
SCHEMBL15458155 0.76 NPC1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 674 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241597-A Platinum complex of 8-hydroxyquinoline derivative and synthetic method and application thereof 玉林师范学院 2025-01-03 CN claimed
CN-110272418-A Triazole compound and its preparation method and application 山东大学 2019-09-24 CN claimed
CN-108084076-A A kind of synthetic method of 5- bromo-7-azaindoles 苏州艾缇克药物化学有限公司 2018-05-29 CN claimed
US-20260146049-A1 SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US disclosed
US-12610949-B2 Heteroaryl-triazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 US disclosed
EP-4704830-A2 MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF Septerna, Inc. (US) 2026-03-11 EP disclosed
US-20260022124-A1 THERAPEUTIC COMPOUNDS AND METHODS UNIV MINNESOTA (US) 2026-01-22 US disclosed
US-20250376475-A1 ION CHANNEL MODULATORS PRAXIS PREC MEDICINES INC (US) 2025-12-11 US disclosed
US-20250345317-A1 New pharmaceutical compounds, methods and uses thereof BBIT THERAPEUTICS LDA (PT) 2025-11-13 US disclosed
EP-4619100-A1 NOVEL BICYCLIC[1,2,4]TRIAZOLONE DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTORS Neurosterix Pharma Sàrl (CH) 2025-09-24 EP disclosed
CN-115605467-B PHD inhibitor compounds, compositions and uses thereof 阿克比治疗有限公司 2025-06-13 CN disclosed
WO-2002026891-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES MOLECULAR PROBES, INC. (US) 2002-04-04 WO disclosed
EP-0509974-B1 Pyrrolo[2,3-b]pyridines having therapeutic activity and a process for the preparation thereof ASTRA AB (SE) 1999-01-13 EP disclosed
US-5439917-A Phenyl-pyrrolo(2,3-b)pyridine antisecretory agent of gastric acid; adenosine triphosphatase enzyme inhibitor AKTIEBOLAGET ASTRA (SE) 1995-08-08 US disclosed
EP-0580616-A1 NEW ACTIVE COMPOUNDS Astra Aktiebolag (SE) 1994-02-02 EP disclosed
CN-1067892-A The preparation method of new pyrrolo-[2,3-b] pyridine derivate ASTRA AB (SE) 1993-01-13 CN disclosed
EP-0509974-A1 Pyrrolo[2,3-b]pyridines having therapeutic activity and a process for the preparation thereof Astra Aktiebolag (SE) 1992-10-21 EP disclosed
WO-1992017477-A1 NEW ACTIVE COMPOUNDS AKTIEBOLAGET ASTRA (SE) 1992-10-15 WO disclosed
US-4260767-A ANTIINFLAMMATORY AMERICAN CYANAMID COMPANY (US) 1981-04-07 US disclosed
EP-0022578-A1 Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1981-01-21 EP disclosed