Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650804 | 0.78 | DRD2 (0.41) | FYNGABRR1DRD2DRD3CA1 | |
| SCHEMBL7855072 | 0.76 | FYN (0.56) | FYNDRD2DRD3OPRK1CA12 | |
| SCHEMBL24650892 | 0.76 | MEN1 (0.41) | FYNDRD2DRD3OPRK1ALDH1A1 | |
| SCHEMBL24650807 | 0.74 | AKR1C4 (0.37) | CA12CA1CA2CA7CA14 | |
| SCHEMBL24650295 | 0.74 | DRD2 (0.45) | GABRR1DRD2DRD3ALDH1A1HSP90AA1 | |
| SCHEMBL24650368 | 0.73 | FYN (0.63) | FYNGABRR1CA12CA1CA2 | |
| SCHEMBL24650358 | 0.72 | FYN (0.47) | FYNGABRR1CA12CA1CA2 | |
| SCHEMBL24650374 | 0.72 | MAPK1 (0.42) | FYNGABRR1DRD2DRD3OPRK1 | |
| SCHEMBL24651078 | 0.71 | F13A1 (0.37) | FYNDRD2DRD3OPRK1MAPT | |
| SCHEMBL24651147 | 0.71 | PTGDR2 (0.40) | FYNDRD2DRD3OPRK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |