Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.36 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650781 | 0.87 | KDM4E (0.40) | DRD2DRD3ADRA1AKDM4EACHE | |
| SCHEMBL24650807 | 0.84 | AKR1C4 (0.37) | SMN1; SMN2KDM4EACHECA1CA2 | |
| SCHEMBL24650874 | 0.82 | HPGD (0.42) | DRD2DRD3SMN1; SMN2KDM4ECDC25B | |
| SCHEMBL24650879 | 0.78 | KDM4E (0.46) | DRD2DRD3ADRA1AKDM4EACHE | |
| SCHEMBL24650802 | 0.78 | FYN (0.42) | DRD2DRD3KDM4ECDC25BCA1 | |
| SCHEMBL24651156 | 0.75 | LMNA (0.43) | DRD2DRD3ADRA1AACHECA1 | |
| SCHEMBL24650895 | 0.74 | DRD2 (0.38) | DRD2DRD3ADRA1AKDM4EACHE | |
| SCHEMBL24650362 | 0.73 | KDM4E (0.47) | ADRA1AKDM4ECA1CA2FYN | |
| SCHEMBL7681591 | 0.73 | CXCR5 (0.48) | SMN1; SMN2KDM4ECDC25BPOLBAKR1C3 | |
| SCHEMBL24650371 | 0.73 | CA12 (0.49) | DRD2DRD3ADRA1ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |