Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651145 | 0.94 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL24650838 | 0.88 | PDE4A (0.42) | CYP1A2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24650814 | 0.86 | MAPT (0.42) | MAPTCYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL24650248 | 0.86 | PTGDR2 (0.41) | MAPTCNR1CNR2TSHRMEN1 | |
| SCHEMBL24650917 | 0.86 | LMNA (0.46) | MAPTCYP1A2TSHRHSP90AB1MEN1 | |
| SCHEMBL24650816 | 0.84 | MAPT (0.41) | MAPTCYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL24650405 | 0.84 | MAPT (0.37) | MAPTCYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL24650998 | 0.82 | MIF (0.36) | MAPTTSHRHSP90AB1 | |
| SCHEMBL24650755 | 0.82 | MAPT (0.45) | MAPTCYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL24651147 | 0.82 | PTGDR2 (0.40) | MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |