Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651147 | 0.93 | PTGDR2 (0.40) | PTGDR2TSHRRAB9AALBHSD17B10 | |
| SCHEMBL24650809 | 0.86 | MAPT (0.46) | TSHRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL24650838 | 0.84 | PDE4A (0.42) | MEN1KMT2AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL24650259 | 0.83 | FFAR1 (0.41) | PTGDR2TSHRFFAR4DRD2DRD3 | |
| SCHEMBL24650746 | 0.83 | ALB (0.40) | TSHRALBFFAR4FYNCNR1 | |
| SCHEMBL24650258 | 0.82 | FFAR4 (0.40) | PTGDR2TSHRFFAR4MEN1ALOX15 | |
| SCHEMBL24651145 | 0.82 | MAPT (0.39) | MEN1KMT2AFYNDRD2DRD3 | |
| SCHEMBL24650753 | 0.81 | FYN (0.47) | PTGDR2TSHRRAB9AFFAR4MEN1 | |
| SCHEMBL24650751 | 0.80 | PTGDR2 (0.40) | PTGDR2TSHRRAB9AFFAR4S1PR5 | |
| SCHEMBL24651078 | 0.80 | F13A1 (0.37) | MEN1KMT2AFYNDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |