Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650889 | 0.90 | KMT2A (0.43) | NQO2MTNR1AMTNR1BBRD4KDM4E | |
| SCHEMBL24651117 | 0.90 | PPARD (0.43) | BRD4PPARDKDM4EGAAHSD17B10 | |
| SCHEMBL24650925 | 0.90 | NQO2 (0.42) | NQO2MTNR1AMTNR1BPPARDKDM4E | |
| SCHEMBL24650264 | 0.88 | BRD4 (0.43) | NQO2MTNR1AMTNR1BBRD4PPARD | |
| SCHEMBL24650866 | 0.86 | BRD4 (0.47) | NQO2MTNR1AMTNR1BBRD4PPARD | |
| SCHEMBL24650483 | 0.85 | BRD4 (0.46) | NQO2MTNR1AMTNR1BBRD4PPARD | |
| SCHEMBL24650926 | 0.85 | MIF (0.42) | NQO2MTNR1AMTNR1BGAAKMT2A | |
| SCHEMBL24650272 | 0.81 | MTNR1A (0.43) | NQO2MTNR1AMTNR1BPPARDHSD17B10 | |
| SCHEMBL3315502 | 0.81 | CYP1A2 (0.45) | GAAHSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL24651106 | 0.81 | NQO2 (0.42) | NQO2MTNR1AMTNR1BPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |