Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650883 | 0.90 | NQO2 (0.40) | KMT2AMTNR1AMTNR1BNQO2BRD4 | |
| SCHEMBL24651110 | 0.90 | KMT2A (0.41) | KMT2AOPRM1BRD4KDM4E | |
| SCHEMBL24650924 | 0.89 | MTNR1A (0.44) | MTNR1AMTNR1BNQO2KYAT1KYAT3 | |
| SCHEMBL24650266 | 0.88 | MTNR1A (0.41) | OPRM1MTNR1AMTNR1BNQO2OPRK1 | |
| SCHEMBL24650484 | 0.85 | BRD4 (0.41) | MTNR1AMTNR1BNQO2BRD4 | |
| SCHEMBL24650926 | 0.85 | MIF (0.42) | KMT2AOPRM1MTNR1AMTNR1BNQO2 | |
| SCHEMBL24650762 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BNQO2KYAT1KYAT3 | |
| SCHEMBL24650925 | 0.83 | NQO2 (0.42) | MTNR1AMTNR1BNQO2KDM4E | |
| SCHEMBL24650334 | 0.81 | OPRM1 (0.39) | KMT2AOPRM1MTNR1AMTNR1BNQO2 | |
| SCHEMBL3315502 | 0.81 | CYP1A2 (0.45) | KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |