Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651088 | 0.96 | SLC22A12 (0.39) | SLC22A12MAPTRXFP1FYNDRD2 | |
| SCHEMBL24650931 | 0.85 | HPGD (0.36) | NR5A2GAAADRA1A | |
| SCHEMBL24651023 | 0.84 | CYP4F2 (0.42) | GAATBXAS1SMN1; SMN2 | |
| SCHEMBL24650953 | 0.82 | ADRA1A (0.44) | SCDDRD2DRD3MAPK1ADRA1A | |
| SCHEMBL24650891 | 0.81 | HSD17B10 (0.41) | MAPTFYNDRD2DRD3GAA | |
| SCHEMBL24651000 | 0.81 | MIF (0.36) | MAPTGAAADRA1A | |
| SCHEMBL24650959 | 0.80 | LTB4R (0.38) | SCDTBXAS1ADRA1A | |
| SCHEMBL24651004 | 0.80 | CYP1A2 (0.39) | GAAMAPK1SMN1; SMN2 | |
| SCHEMBL24650946 | 0.79 | F13A1 (0.42) | MAPTRXFP1SCDF13A1DRD2 | |
| SCHEMBL24650257 | 0.77 | DRD3 (0.35) | FYNDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |