Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651003 | 0.97 | ADRA1A (0.57) | ADRA1AEPHX2PDE4DMAPTMMP2 | |
| SCHEMBL24650989 | 0.91 | ADRA1A (0.58) | ADRA1APDE4DMMP2ANPEP | |
| SCHEMBL24651022 | 0.89 | ADRA1A (0.50) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL24651020 | 0.89 | ADRA1A (0.40) | ADRA1AHPGDEPHX2CNR1CNR2 | |
| SCHEMBL24650958 | 0.88 | ADRA1A (0.55) | ADRA1A | |
| SCHEMBL24651009 | 0.86 | ADRA1A (0.42) | ADRA1AEPHX2PDE4DMAPTMEN1 | |
| SCHEMBL24651086 | 0.85 | ADRA1A (0.58) | ADRA1A | |
| SCHEMBL24650821 | 0.84 | ADRA1A (0.57) | ADRA1AHPGDCNR1CNR2PDE4D | |
| SCHEMBL24651013 | 0.83 | MIF (0.39) | ADRA1AHPGDEPHX2MAPTALDH1A1 | |
| SCHEMBL24650490 | 0.82 | ADRA1A (0.62) | ADRA1AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |