Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650459 | 0.87 | ADRA1A (0.45) | ADRA1ACYP1A2MTNR1AMTNR1BMEN1 | |
| SCHEMBL24650922 | 0.87 | ADRA1A (0.64) | ADRA1ACYP1A2DRD2DRD3AADAT | |
| SCHEMBL24650989 | 0.86 | ADRA1A (0.58) | ADRA1ACYP1A2 | |
| SCHEMBL24651003 | 0.85 | ADRA1A (0.57) | ADRA1ACYP1A2MTNR1AMTNR1BKMT2A | |
| SCHEMBL24650476 | 0.84 | ALDH1A1 (0.44) | ADRA1AMAPT | |
| SCHEMBL24651027 | 0.82 | ADRA1A (0.54) | ADRA1AMEN1KMT2AMAPT | |
| SCHEMBL24650313 | 0.82 | ADRA1A (0.62) | ADRA1ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL24651146 | 0.80 | ADRA1A (0.58) | ADRA1ACYP1A2DRD2DRD3MAPT | |
| SCHEMBL24650821 | 0.79 | ADRA1A (0.57) | ADRA1ACYP1A2DRD2DRD3MEN1 | |
| SCHEMBL14712035 | 0.79 | LMNA (0.40) | ADRA1AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |