Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 12/20 | 0.59 |
| ▸ | EIF2AK3 | Q9NZJ5 | 11/20 | 0.59 |
| ▸ | EIF2AK2 | P19525 | 6/20 | 0.59 |
| ▸ | EIF2AK1 | Q9BQI3 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | YES1 | P07947 | 2/20 | 0.48 |
| ▸ | RET | P07949 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.48 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.48 |
| ▸ | MERTK | Q12866 | 2/20 | 0.48 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120797 | 0.94 | EIF2AK3 (0.58) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL24651187 | 0.94 | EIF2AK3 (0.58) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL30121061 | 0.92 | RIPK1 (0.57) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL24651200 | 0.92 | RIPK1 (0.57) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL30120824 | 0.92 | EIF2AK3 (0.56) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL24650635 | 0.92 | EIF2AK3 (0.56) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL30120746 | 0.91 | EIF2AK3 (0.56) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL24651061 | 0.91 | EIF2AK3 (0.56) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL30120836 | 0.90 | RIPK1 (0.54) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 | |
| SCHEMBL24650632 | 0.87 | EIF2AK3 (0.57) | RIPK1EIF2AK3EIF2AK2EIF2AK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |