SCHEMBL2465307

SCHEMBL2465307

C=C(C)C(=O)OCCN(C)C=O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
USP2 O75604 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12320110 0.88 TSHR (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL788116 0.83 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9862710 0.81 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL712423 0.80 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14984 0.80 CHRM2 (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28671752 0.80 CHRM2 (0.54) THRBTSHRALDH1A1POLBAPEX1
Ammonia Solution, Strong SCHEMBL8139148 0.79 CHRM2 (0.52) THRBTSHRALDH1A1POLBAPEX1
Fluoride SCHEMBL1255040 0.79 CHRM2 (0.52) THRBTSHRALDH1A1POLBAPEX1
Bromide SCHEMBL1255341 0.79 CHRM2 (0.52) THRBTSHRALDH1A1POLBAPEX1
Methyl Alcohol SCHEMBL21326731 0.79 CHRM2 (0.52) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499923-B1 Dental adhesive BAYER AG (DE) 1996-01-24 EP claimed
US-5354827-A (Meth)acrylic acid esters containign formamide groups, crosslinking agents, solvents and acid BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US claimed
EP-0499923-A1 Dental adhesive Heraeus Kulzer GmbH & Co.KG (DE) 1992-08-26 EP claimed
JP-5070317-A None JP disclosed
CN-114174238-B Low odor and low emission particulate materials and related coatings 赛德克公众有限公司 2023-05-05 CN disclosed
CN-114174238-A Particulate materials and related coatings, especially architectural element coatings, with low odor and low emissions, e.g. floor coatings based on free radical polymerization 赛德克公众有限公司 2022-03-11 CN disclosed
EP-2109659-B1 DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS LUBRIZOL CORP (US) 2019-06-12 EP disclosed
US-8722600-B2 Polymers with H-bridge forming functionalities for improving anti-wear protection EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-05-13 US disclosed
US-20130131254-A1 PROCESS FOR PRODUCING POLYMER DISPERSIONS EVONIK OIL ADDITIVES GMBH (DE) 2013-05-23 US disclosed
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US disclosed
US-20110230378-A1 IMPROVED POLYMER DISPERSIONS EVONIK ROHMAX ADDITIVES GMBH (DE) 2011-09-22 US disclosed
US-5354827-A (Meth)acrylic acid esters containign formamide groups, crosslinking agents, solvents and acid BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5277739-A Applying a curable adhesive having (meth)acrylic acid esters with a formamide group BAYER AKTIENGESELLSCHAFT (DE) 1994-01-11 US disclosed
EP-0355562-B1 Adhesive for treating collageneous material BAYER AG (DE) 1994-01-05 EP disclosed
JP-H0570317-A DENTAL ADHESIVE BAYER AG 1993-03-23 JP disclosed
EP-0499923-A1 Dental adhesive Heraeus Kulzer GmbH & Co.KG (DE) 1992-08-26 EP disclosed
EP-0355562-A2 Adhesive for treating collageneous material BAYER AG (DE) 1990-02-28 EP disclosed
US-4009195-A FROM 1-ALKENES AND ACRYLIC ACID DERIVATIVES ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed
US-3994958-A OF 1-ALKENES AND ACRYLIC ACID DERIVATIVES ROHM AND HAAS COMPANY (US) 1976-11-30 US disclosed
US-3968148-A Copolymers of 1-alkenes and acrylic acid derivatives ROHM AND HAAS COMPANY (US) 1976-07-06 US disclosed