Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862710 | 0.98 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9312199 | 0.93 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL12319436 | 0.92 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2465307 | 0.83 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL13199264 | 0.81 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL746457 | 0.79 | THRB (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL3283075 | 0.78 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL28671752 | 0.78 | CHRM2 (0.54) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL712423 | 0.78 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL14984 | 0.78 | CHRM2 (0.54) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557893-B2 | Substituted saccharide compounds and dental compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-15 | — | — | US | disclosed |
| EP-2616476-A2 | SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS | 3M Innovative Properties Company (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20130164709-A1 | SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-06-27 | — | — | US | disclosed |
| WO-2012036838-A2 | SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130164709-A1 | SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS | SI, ACMSD, SORD | THRB 4181/4885TSHR 4249/4885POLB 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.